HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30948266, 29395067, 36232890
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0005783 - endoplasmic reticulum
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 1430
+	Hs
		944943 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		YTDC2_HUMAN (1-1430): 0: 1502: 100.00
+	Hs
		269881 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		YTDC2_HUMAN (1-1430): 0: 1502: 100.00
+	Hs
		322625 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX8_HUMAN (25-482): 1.24e-127: 428: 22.61
+	Hs
		322947 STAU1_HUMAN (1-577): 0: 524: 100.00		PRP16_HUMAN (25-482): 4.04e-118: 402: 22.57
+	Hs
		195300 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65
+	Hs
		323126 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63
+	Hs
		323137 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX35_HUMAN (160-482): 4.45e-101: 341: 26.23
+	Hs
		322813 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32
+	Hs
		322523 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		322762 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23
+	Hs
		322802 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Hs
		195387 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65
+	Hs
		994297 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		877250 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		1220242 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40
+	Hs
		994267 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		269708 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		1183954 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Hs
		944842 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Hs
		269780 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39