HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33957083, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0051087 - protein-folding chaperone binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 337
+	Hs
		279268 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJB5_HUMAN (1-337): 1.41e-131: 380: 60.92
+	Hs
		323596 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		243235 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		323608 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		323926 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJA4_HUMAN (5-336): 1.32e-116: 344: 31.12
+	Hs
		324094 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DJB11_HUMAN (2-334): 6.07e-99: 298: 31.34
+	Dm
		1096123 Q9VUQ1_DROME (7-178): 4.48e-73: 223: 35.64		DNAJ1_DROME (1-335): 6.88e-117: 342: 54.87
+	Dm
		1096098 Q95RY2_DROME (25-178): 8.85e-65: 202: 36.15		DNAJ1_DROME (1-335): 6.88e-117: 342: 54.87