HitPredict

Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: CRYAA (P02489)
Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) (Heat shock protein family B member 4) [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168); Alpha-crystallin A(1-162)]
Gene: CRYAA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 33961781, 32814053
Identification Methods affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 575
Hs

1 173
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Last updated: 15 Jul 2024