Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 29568061, 24914854, 26535916, 20111043, 17094969
Identification Methods proximity labelling technology, affinity chromatography technology, x-ray crystallography, biochemical, pull down, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AIF_C~AIF_C, AIF_C~Pyr_redox_2, Pyr_redox_2~Pyr_redox_2
Common GO terms GO:0002931 - response to ischemia
GO:0003677 - DNA binding
GO:0003954 - NADH dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 30 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 613
Hs

1 613
+ Mm
+ Hs
+ Dm
+ Dm
+ Rn
+ Hs
+ Hs
+ At
+ Ec
+ At
+ Sc
+ Ec
+ Mp
+ Sp
+ Pa

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024