HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 28754671, 30461308, 35941108
Identification Methods enzymatic study, protein complementation assay, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~Pkinase_C, Pkinase~UBA, UBA~UBA
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000287 - magnesium ion binding
GO:0000819 - sister chromatid segregation
GO:0000922 - spindle pole
and 29 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 1130
+ Hs
+ Hs
+ Hs
+ Hs
+ Ps
+ At
+ Sc
+ Hs
+ Sp
+ Rn
+ Hs
+ Hs
+ At
+ Hs
+ Sc
+ At
+ Sl
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024