Protein: L2GL1
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)

Gene: L2GL1, LLGL1
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q15334

Gene Ontology (top 5):
GO:0000137 - Golgi cis cisterna
GO:0000139 - Golgi membrane
GO:0005096 - GTPase activator activity
GO:0005198 - structural molecule activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1071538

L2GL2
LLGL scribble cell polarity complex component 2

2

3

High-throughput

0.776

High

983844

KPCZ
Protein kinase C zeta type

8

10

High-throughput

0.749

High

784012

KPCI
Protein kinase C iota type

7

9

Small-scale

0.744

High

1071568

PAR6B
Partitioning defective 6 homolog beta

6

8

High-throughput

0.735

High

350186

RASK
GTPase KRas

4

7

High-throughput

0.676

High

243415

DNJA2
DnaJ homolog subfamily A member 2

3

5

High-throughput

0.650

High

1036593

SQSTM
Sequestosome-1

3

1

High-throughput

0.650

High

1071549

KBTB7
Kelch repeat and BTB domain-containing protein 7

4

2

High-throughput

0.636

High

1071578

PAR6A
Partitioning defective 6 homolog alpha

2

8

High-throughput

0.628

High

1071548

PARD3
Partitioning defective 3 homolog

2

1

High-throughput

0.611

High

1071567

PAR6G
Partitioning defective 6 homolog gamma

2

8

High-throughput

0.601

High

1041626

CUL3
Cullin-3

2

0

High-throughput

0.585

High

227518

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

348672

RASN
GTPase NRas

2

7

High-throughput

0.584

High

384883

NTRK1
High affinity nerve growth factor receptor

2

4

High-throughput

0.584

High

507028

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

915693

RHOB
Rho-related GTP-binding protein RhoB

2

13

High-throughput

0.584

High

1071592

DMXL1
DmX-like protein 1

1

0

High-throughput

0.578

High

497062

TAU
Microtubule-associated protein tau

2

0

Small-scale

0.576

High

1071565

RANB9
Ran-binding protein 9

1

0

Small-scale

0.549

High

1071593

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

2

1

High-throughput

0.549

High

1030142

STX3
Syntaxin-3

1

16

High-throughput

0.536

High

1071547

ARRD2
Arrestin domain-containing protein 2

1

4

High-throughput

0.536

High

1071552

ARL11
ADP-ribosylation factor-like protein 11

1

2

High-throughput

0.536

High

1071556

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1071557

ARRD3
Arrestin domain-containing protein 3

1

4

High-throughput

0.536

High

1071564

TRIB1
Tribbles homolog 1

1

3

High-throughput

0.536

High

674850

AGTR1
Type-1 angiotensin II receptor

1

0

High-throughput

0.518

High

1071586

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.517

High

323770

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

575744

VINC
Vinculin

1

0

High-throughput

0.513

High

791577

HD
Huntingtin

1

0

High-throughput

0.513

High

863234

COPB
Coatomer subunit beta

1

0

High-throughput

0.513

High

1071545

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1071560

SPB12
Serpin B12

1

0

High-throughput

0.513

High

1071569

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

475794

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

1069348

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.489

High

1071570

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

High-throughput

0.489

High

132315

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.486

High

120451

RHOD
Rho-related GTP-binding protein RhoD

1

15

High-throughput

0.479

High

178544

STX7
Syntaxin-7

1

12

High-throughput

0.479

High

212839

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

318139

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

338462

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

349333

RASH
GTPase HRas

1

5

High-throughput

0.479

High

411730

LCK
Tyrosine-protein kinase Lck

1

1

High-throughput

0.479

High

433771

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

434202

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

4

High-throughput

0.479

High

435650

IGF1R
Insulin-like growth factor 1 receptor

1

4

High-throughput

0.479

High

436316

RHOC
Rho-related GTP-binding protein RhoC

1

11

High-throughput

0.479

High

527462

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

545393

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

564540

RHOQ
Rho-related GTP-binding protein RhoQ

1

13

High-throughput

0.479

High

567067

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

568673

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.479

High

592269

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

674437

UFO
Tyrosine-protein kinase receptor UFO

1

2

Small-scale

0.479

High

725167

MYH10
Myosin-10

1

1

Small-scale

0.479

High

779456

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

793319

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

844534

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

845496

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

852487

RND2
Rho-related GTP-binding protein RhoN

1

16

High-throughput

0.479

High

876390

AFAD
Afadin

1

2

High-throughput

0.479

High

892387

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

894033

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

895085

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.479

High

900495

RHOA
Transforming protein RhoA

1

12

High-throughput

0.479

High

901162

RND3
Rho-related GTP-binding protein RhoE

1

17

High-throughput

0.479

High

912915

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

925296

RAC1
Ras-related C3 botulinum toxin substrate 1

1

12

High-throughput

0.479

High

951010

RHOG
Rho-related GTP-binding protein RhoG

1

11

High-throughput

0.479

High

1017639

STX4
Syntaxin-4

1

16

High-throughput

0.479

High

1070201

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1071533

RHOH
Rho-related GTP-binding protein RhoH

1

13

High-throughput

0.479

High

1071534

NTRK3
NT-3 growth factor receptor

1

4

High-throughput

0.479

High

1071535

NTRK2
BDNF/NT-3 growth factors receptor

1

4

High-throughput

0.479

High

1071537

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1071540

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1071541

RHOU
Rho-related GTP-binding protein RhoU

1

15

High-throughput

0.479

High

1071543

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

1

High-throughput

0.479

High

1071546

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1071550

RND1
Rho-related GTP-binding protein Rho6

1

17

High-throughput

0.479

High

1071558

RHOV
Rho-related GTP-binding protein RhoV

1

13

High-throughput

0.479

High

1071561

FMNL2
Formin-like protein 2

1

1

High-throughput

0.479

High

1071571

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1071573

RHOJ
Rho-related GTP-binding protein RhoJ

1

13

High-throughput

0.479

High

1071576

RHOF
Rho-related GTP-binding protein RhoF

1

14

High-throughput

0.479

High

1071577

E41LA
Band 4.1-like protein 4A

1

1

High-throughput

0.479

High

1071579

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

1071581

RN146
E3 ubiquitin-protein ligase RNF146

1

1

Small-scale

0.479

High

1071585

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1071589

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

48362

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.458

High

149639

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.458

High

205421

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

279561

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

346845

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

418302

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

521946

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

577023

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.458

High

670036

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

825423

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

914083

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

940427

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

974831

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1034864

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1071536

OCLN
Occludin

1

0

High-throughput

0.458

High

1071539

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.458

High

1071553

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

1071562

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1071566

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.458

High

1071574

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1071575

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1071583

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

306184

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.445

High

636338

DNJB1
DnaJ homolog subfamily B member 1

1

5

High-throughput

0.445

High

681458

DNJA1
DnaJ homolog subfamily A member 1

1

5

High-throughput

0.445

High

891158

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

High-throughput

0.445

High

1071580

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.445

High

1071587

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.445

High

1071588

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.445

High

1071590

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.445

High

583482

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

908582

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1063799

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.437

High

1071551

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1071584

DNJ5B
DnaJ homolog subfamily C member 5B

1

3

High-throughput

0.437

High

382427

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.426

High

874960

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1071572

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

3

High-throughput

0.407

High

1071591

SGT1
Protein SGT1 homolog

1

1

High-throughput

0.407

High

552786

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.305

High

850057

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

Small-scale

0.292

High

676673

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

0

High-throughput

0.279

Low

1071559

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.279

Low

1071582

SMAL1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

1

0

High-throughput

0.279

Low

1071594

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.279

Low

305457

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

651268

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

720526

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1071532

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.249

Low

1071542

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1071544

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1071554

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1071563

CIC
Protein capicua homolog

1

0

High-throughput

0.249

Low

1071555

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024