Interactor 1: UBR5 (O95071)
E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein)
Gene: UBR5
Interactor 2: PTTG1 (O95997)
Securin (Esp1-associated protein) (Pituitary tumor-transforming gene 1 protein) (Tumor-transforming protein 1) (hPTTG)
Gene: PTTG1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37409633 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006281 - DNA repair |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
