HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 247
+	Hs
		325680 LATS1_HUMAN (1-1130): 0: 934: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		325701 LATS1_HUMAN (1-1130): 0: 934: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		325641 LATS1_HUMAN (1-1130): 0: 934: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		325683 LATS1_HUMAN (1-1130): 0: 934: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		325635 LATS1_HUMAN (1-1130): 0: 934: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		325642 LATS1_HUMAN (1-1130): 0: 934: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		905160 LATS2_HUMAN (13-1121): 0: 751: 49.61		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982537 LATS2_HUMAN (13-1121): 0: 751: 49.61		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Zm
		45993 A0A1Q0ZG94_MAIZE (2-1105): 0: 728: 19.37		B6SRI4_MAIZE (2-245): 2.63e-140: 395: 60.16
+	Hs
		927572 LATS2_HUMAN (13-1121): 0: 751: 49.61		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		910180 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	At
		221452 PHOT1_ARATH (156-1060): 6.3e-158: 497: 17.08		14334_ARATH (4-244): 5e-140: 395: 60.91
+	Hs
		904584 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	At
		221451 PHOT1_ARATH (156-1060): 6.3e-158: 497: 17.08		14335_ARATH (3-244): 5.67e-136: 385: 59.02
+	Hs
		681770 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		681766 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		683831 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		683365 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927070 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		681682 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16