Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: MARK1 (Q9P0L2)
Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)
Gene: MARK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 24362629
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KA1~Pkinase, Pkinase~Pkinase, Pkinase~UBA, Pkinase~Pkinase_C, KA1~UBA, UBA~UBA
Common GO terms GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 795
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
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+ Sc

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Last updated: 15 Jul 2024