Interactor 1: MFN2 (O95140)
Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2)
Gene: MFN2
Interactor 2: MARH5 (Q9NX47)
E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCHF5)
Gene: MARCHF5
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.60 | 0.751 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26210454, 32877691, 23727017, 26186194, 28514442, 33961781, 34964862, 16936636 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, enzymatic study, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
