HitPredict

Interactor 1: CBX7 (O95931)
Chromobox protein homolog 7
Gene: CBX7

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	18927235
Identification Methods	protein complementation assay, bimolecular fluorescence complementation
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 251 Hs			1 136
+	Hs
		327837 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		327844 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		327849 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Mm
		223226 CBX4_MOUSE (1-242): 9.5e-58: 194: 33.60		H33_MOUSE (1-136): 1.12e-59: 182: 100.00
+	Hs
		123231 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		123236 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		123254 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		123269 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Hs
		111555 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		K7EK07_HUMAN (1-132): 7.81e-58: 177: 100.00
+	Hs
		935387 CDYL_HUMAN (2-250): 1.53e-48: 170: 19.93		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952709 CDYL_HUMAN (2-250): 1.53e-48: 170: 19.93		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		1086356 CDYL_HUMAN (2-250): 1.53e-48: 170: 19.93		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Dm
		356104 Q9VCU6_DROME (8-221): 1.01e-48: 162: 26.01		H3_DROME (1-136): 5.32e-59: 180: 97.06
+	Hs
		934987 CDYL2_HUMAN (9-215): 7.04e-42: 151: 16.52		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		1086221 CDYL2_HUMAN (9-215): 7.04e-42: 151: 16.52		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		800341 CBX5_HUMAN (11-165): 5.63e-43: 146: 20.48		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		800347 CBX5_HUMAN (11-165): 5.63e-43: 146: 20.48		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		800397 CBX5_HUMAN (11-165): 5.63e-43: 146: 20.48		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		800434 CBX5_HUMAN (11-165): 5.63e-43: 146: 20.48		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Hs
		800317 CBX5_HUMAN (11-165): 5.63e-43: 146: 20.48		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76