Protein: MLP3C
Microtubule-associated protein 1 light chain 3 gamma (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (Microtubule-associated proteins 1A/1B light chain 3C) (MAP1A/MAP1B LC3 C) (MAP1A/MAP1B light chain 3 C)

Gene: MLP3C, MAP1LC3C
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9BXW4

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0000423 - mitophagy
GO:0005776 - autophagosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1417426

ATG4B
Cysteine protease ATG4B

5

20

Small-scale

0.928

High

334234

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

2

18

Small-scale

0.825

High

1290293

KBTB6
Kelch repeat and BTB domain-containing protein 6

2

20

Small-scale

0.817

High

1358844

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

20

Small-scale

0.817

High

1108111

SQSTM
Sequestosome-1

13

20

Small-scale

0.757

High

1417407

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

2

15

Small-scale

0.755

High

1095790

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

7

18

Small-scale

0.751

High

279216

ULK1
Serine/threonine-protein kinase ULK1

5

13

Small-scale

0.716

High

271572

ATG13
Autophagy-related protein 13

4

7

Small-scale

0.707

High

328139

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

14

High-throughput

0.691

High

952326

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

14

High-throughput

0.691

High

1290960

TAXB1
Tax1-binding protein 1

4

18

Small-scale

0.688

High

1417410

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

20

High-throughput

0.681

High

1351964

RBCC1
RB1-inducible coiled-coil protein 1

3

15

Small-scale

0.670

High

1128820

NBR1
Next to BRCA1 gene 1 protein

3

12

Small-scale

0.667

High

1138015

TNIP1
TNFAIP3-interacting protein 1

3

16

High-throughput

0.658

High

977817

ACTA
Actin, aortic smooth muscle

3

15

High-throughput

0.657

High

1097728

STK3
Serine/threonine-protein kinase 3

2

14

Small-scale

0.636

High

1410935

FYCO1
FYVE and coiled-coil domain-containing protein 1

2

14

Small-scale

0.636

High

861760

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

9

Small-scale

0.629

High

1412230

ATGA1
Autophagy-related protein 101

2

5

Small-scale

0.629

High

1187135

TBC25
TBC1 domain family member 25

2

20

High-throughput

0.606

High

1253036

RUFY4
RUN and FYVE domain-containing protein 4

2

20

High-throughput

0.606

High

1382488

T53I1
Tumor protein p53-inducible nuclear protein 1

2

8

High-throughput

0.606

High

1316767

WDFY3
WD repeat and FYVE domain-containing protein 3

1

20

Small-scale

0.597

High

1386565

OPTN
Optineurin

2

13

Small-scale

0.594

High

1227392

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.586

High

635095

CAN3
Calpain-3

2

0

High-throughput

0.580

High

1340700

RHXF1
Rhox homeobox family member 1

2

0

High-throughput

0.580

High

1417421

GMEB2
Glucocorticoid modulatory element-binding protein 2

2

0

High-throughput

0.580

High

1007251

TCPB
T-complex protein 1 subunit beta

1

20

Small-scale

0.561

High

1200927

WDR81
WD repeat-containing protein 81

1

18

Small-scale

0.561

High

600371

ZNF24
Zinc finger protein 24

2

3

High-throughput

0.553

High

770911

OPRM
Mu-type opioid receptor

2

4

High-throughput

0.553

High

1309156

MISP
Mitotic interactor and substrate of PLK1

2

1

High-throughput

0.553

High

1379856

TSR2
Pre-rRNA-processing protein TSR2 homolog

2

2

High-throughput

0.553

High

1108457

MTX1
Metaxin-1

2

3

Small-scale

0.543

High

943123

STX17
Syntaxin-17

1

0

Small-scale

0.537

High

907567

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.536

High

1086306

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.536

High

1337313

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

High-throughput

0.536

High

1417412

ATG5
Autophagy protein 5

1

9

High-throughput

0.536

High

1417417

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

19

High-throughput

0.536

High

49999

IRGM
Immunity-related GTPase family M protein

1

0

Small-scale

0.529

High

134140

IPO5
Importin-5

1

10

High-throughput

0.527

High

175526

TCPR2
Tectonin beta-propeller repeat-containing protein 2

1

4

High-throughput

0.527

High

276171

NIPS2
Protein NipSnap homolog 2

1

10

High-throughput

0.527

High

1350557

NEK9
Serine/threonine-protein kinase Nek9

1

19

High-throughput

0.527

High

1359828

RASF5
Ras association domain-containing protein 5

1

13

High-throughput

0.527

High

1361115

DAAF4
Dynein axonemal assembly factor 4

1

9

High-throughput

0.527

High

1417416

RASF1
Ras association domain-containing protein 1

1

16

High-throughput

0.527

High

1417424

TBD2B
TBC1 domain family member 2B

1

20

High-throughput

0.527

High

1114199

CUL3
Cullin-3

1

5

Small-scale

0.516

High

1149181

SF3A1
Splicing factor 3A subunit 1

1

13

High-throughput

0.506

High

194786

MEFV
Pyrin

1

12

Small-scale

0.501

High

278421

NCOR1
Nuclear receptor corepressor 1

1

12

High-throughput

0.501

High

531139

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

6

High-throughput

0.501

High

623516

RO52
E3 ubiquitin-protein ligase TRIM21

1

12

Small-scale

0.501

High

927124

ATX3
Ataxin-3

1

2

Small-scale

0.501

High

1030682

ANK2
Ankyrin-2

1

15

Small-scale

0.501

High

1091452

ANK3
Ankyrin-3

1

15

Small-scale

0.501

High

1093171

STK4
Serine/threonine-protein kinase 4

1

15

High-throughput

0.501

High

1093412

TRI32
E3 ubiquitin-protein ligase TRIM32

1

12

Small-scale

0.501

High

1125213

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

17

Small-scale

0.501

High

1129872

EPN4
Clathrin interactor 1

1

12

High-throughput

0.501

High

1158518

CDC37
Hsp90 co-chaperone Cdc37

1

5

High-throughput

0.501

High

1180314

ATG2A
Autophagy-related protein 2 homolog A

1

8

High-throughput

0.501

High

1220768

RN123
E3 ubiquitin-protein ligase RNF123

1

20

High-throughput

0.501

High

1235676

NIPBL
Nipped-B-like protein

1

20

High-throughput

0.501

High

1353504

FNIP1
Folliculin-interacting protein 1

1

5

High-throughput

0.501

High

1356988

PDC6I
Programmed cell death 6-interacting protein

1

6

High-throughput

0.501

High

1366342

FAN
Protein FAN

1

18

High-throughput

0.501

High

1417411

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

19

High-throughput

0.501

High

1417422

DP13A
DCC-interacting protein 13-alpha

1

6

High-throughput

0.501

High

568695

GYS1
Glycogen [starch] synthase, muscle

1

6

High-throughput

0.479

High

610870

TCPA
T-complex protein 1 subunit alpha

1

16

Small-scale

0.479

High

646930

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

4

Small-scale

0.479

High

801506

HSPA9
Stress-70 protein, mitochondrial

1

20

Small-scale

0.479

High

821550

TCPZ
T-complex protein 1 subunit zeta

1

15

Small-scale

0.479

High

882135

TCPG
T-complex protein 1 subunit gamma

1

17

Small-scale

0.479

High

1143513

PCM1
Pericentriolar material 1 protein

1

4

Small-scale

0.479

High

1385138

MOAP1
Modulator of apoptosis 1

1

2

Small-scale

0.479

High

1402031

FNBP1
Formin-binding protein 1

1

3

High-throughput

0.479

High

1405327

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

6

High-throughput

0.479

High

1417415

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

7

Small-scale

0.479

High

1417418

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

17

Small-scale

0.479

High

1417419

ANFY1
Rabankyrin-5

1

15

High-throughput

0.479

High

1417425

RBGP1
Rab GTPase-activating protein 1

1

20

High-throughput

0.479

High

123277

PDLI1
PDZ and LIM domain protein 1

1

3

High-throughput

0.457

High

634611

LMNB1
Lamin-B1

1

20

Small-scale

0.457

High

1340929

NCOA7
Nuclear receptor coactivator 7

1

4

High-throughput

0.457

High

1349321

TBC15
TBC1 domain family member 15

1

20

High-throughput

0.457

High

1417427

SAM50
Sorting and assembly machinery component 50 homolog

1

4

Small-scale

0.457

High

935969

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

6

High-throughput

0.437

High

1121734

SAFB2
Scaffold attachment factor B2

1

20

High-throughput

0.437

High

1417423

CCPG1
Cell cycle progression protein 1

1

6

High-throughput

0.437

High

1417408

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

7

Small-scale

0.408

High

650939

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

20

High-throughput

0.407

High

1417420

ABC3B
DNA dC->dU-editing enzyme APOBEC-3B

1

3

High-throughput

0.407

High

1417413

BICC1
Protein bicaudal C homolog 1

1

16

High-throughput

0.373

High

1417414

RESF1
Retroelement silencing factor 1

1

4

High-throughput

0.373

High

220414

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.316

High

1417409

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025