HitPredict

Interactor 1: CBX7 (O95931)
Chromobox protein homolog 7
Gene: CBX7

Interactor 2: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21282530
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CBX7_C~RAWUL
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031519 - PcG protein complex GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 251 Hs			1 256
+	Hs
		327830 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38
+	Hs
		327831 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		PCGF2_HUMAN (1-244): 2.94e-56: 185: 29.13
+	Hs
		327845 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04
+	Hs
		327861 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25
+	Hs
		327858 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		RING2_HUMAN (2-252): 1.71e-41: 146: 17.59
+	Hs
		327860 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		123273 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00
+	Hs
		327842 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		RING1_HUMAN (2-142): 1.22e-34: 129: 20.42
+	Hs
		123174 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		RO52_HUMAN (3-242): 5.86e-56: 187: 13.79
+	Hs
		123193 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38
+	Hs
		123194 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PCGF2_HUMAN (1-244): 2.94e-56: 185: 29.13
+	Mm
		223225 CBX4_MOUSE (1-242): 9.5e-58: 194: 33.60		PCGF2_MOUSE (1-244): 1.85e-53: 177: 28.35
+	Hs
		123257 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04
+	Mm
		223231 CBX4_MOUSE (1-242): 9.5e-58: 194: 33.60		RING2_MOUSE (2-252): 2.64e-41: 146: 17.59
+	Hs
		123317 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25
+	Dr
		1186372 Q804D1_DANRE (1-175): 1.64e-41: 149: 35.75		BMI1B_DANRE (1-230): 1.36e-57: 188: 28.69
+	Hs
		123308 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		RING2_HUMAN (2-252): 1.71e-41: 146: 17.59
+	Hs
		123312 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		123243 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		RING1_HUMAN (2-142): 1.22e-34: 129: 20.42
+	Mm
		1164651 Q6TKP2_MOUSE (1-198): 5.13e-41: 150: 32.29		RING2_MOUSE (2-252): 2.64e-41: 146: 17.59