HitPredict

Interactor 1: FBLN4 (O95967)
EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1)
Gene: EFEMP2

Interactor 2: LCE3D (Q9BYE3)
Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B)
Gene: LCE3D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 92
+	Hs
		327994 FBLN4_HUMAN (1-443): 1.79e-69: 228: 100.00		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		327993 FBLN4_HUMAN (1-443): 1.79e-69: 228: 100.00		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		957285 FBLN2_HUMAN (45-399): 9.48e-20: 94.5: 24.68		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		1154501 TEN4_HUMAN (235-412): 3.22e-16: 83.7: 8.21		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		1016989 FBLN3_HUMAN (6-244): 1.09e-11: 68.7: 22.01		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00