HitPredict

Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.745

The method score is based on:

Property Details
Experiments 12354758, 24981860, 25247294, 28977666, 32744500, 33283408, 21670149, 25123934
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 8 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 291
Hs

1 1912
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024