HitPredict

Interactor 1: TOP3B (O95985)
DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1)
Gene: TOP3B

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34709727
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0006310 - DNA recombination
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 616
+	Hs
		651129 TOP3A_HUMAN (1-843): 0: 878: 31.59		RFA1_HUMAN (1-616): 0: 781: 100.00