HitPredict

Interactor 1: TOP3B (O95985)
DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1)
Gene: TOP3B

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	29395067, 34709727
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 599
+	Hs
		328979 TOP3B_HUMAN (1-862): 0: 1242: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		328923 TOP3B_HUMAN (1-862): 0: 1242: 100.00		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		328807 TOP3B_HUMAN (1-862): 0: 1242: 100.00		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01