HitPredict

Interactor 1: TOM40 (O96008)
Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5)
Gene: TOMM40

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29360040, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 207
+	Hs
		330656 TOM40_HUMAN (1-361): 1.42e-121: 356: 100.00		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		330722 TOM40_HUMAN (1-361): 1.42e-121: 356: 100.00		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		1281671 TM40L_HUMAN (57-361): 5.66e-109: 322: 61.31		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		799962 VDAC2_HUMAN (67-360): 7.67e-85: 260: 10.82		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		918970 VDAC3_HUMAN (77-360): 1.86e-84: 259: 9.97		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		799950 VDAC2_HUMAN (67-360): 7.67e-85: 260: 10.82		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		601201 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		601361 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		601179 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		799949 VDAC2_HUMAN (67-360): 7.67e-85: 260: 10.82		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Hs
		601178 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44