HitPredict

Interactor 1: PAK4 (O96013)
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)
Gene: PAK4

Interactor 2: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 591 Hs			1 1369
+	Hs
		528371 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH6_HUMAN (726-1318): 6.46e-24: 112: 11.52
+	Hs
		528369 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH6_HUMAN (726-1318): 6.46e-24: 112: 11.52
+	Hs
		522610 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH7_HUMAN (1006-1369): 1.13e-19: 98.4: 14.56
+	Hs
		528409 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH8_HUMAN (681-1253): 2e-19: 97.6: 10.92
+	Hs
		522609 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH7_HUMAN (1006-1369): 1.13e-19: 98.4: 14.56
+	Hs
		528408 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH8_HUMAN (681-1253): 2e-19: 97.6: 10.92
+	Hs
		522546 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH1_HUMAN (698-1170): 2.35e-14: 81: 7.93
+	Hs
		522545 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH1_HUMAN (698-1170): 2.35e-14: 81: 7.93
+	Hs
		1027452 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH2_HUMAN (706-1121): 2.6e-11: 71: 7.43
+	Hs
		1023137 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH2_HUMAN (706-1121): 2.6e-11: 71: 7.43
+	Hs
		1027453 STK3_HUMAN (289-588): 1.76e-123: 374: 35.43		MYH13_HUMAN (1067-1368): 2.88e-09: 64.1: 13.25
+	Hs
		254459 KS6A3_HUMAN (265-591): 5.2e-113: 355: 24.27		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		1023138 STK4_HUMAN (298-588): 1.44e-122: 372: 35.50		MYH13_HUMAN (1067-1368): 2.88e-09: 64.1: 13.25
+	Hs
		1217590 M4K3_HUMAN (316-574): 1.61e-52: 195: 40.00		ITSN2_HUMAN (755-1327): 1.16e-31: 137: 14.65
+	Hs
		277606 PAK3_HUMAN (3-210): 5.28e-25: 111: 19.56		ITSN1_HUMAN (748-1251): 2.26e-22: 107: 14.09
+	Hs
		725152 PAK2_HUMAN (8-161): 8.45e-26: 113: 16.67		MYH10_HUMAN (928-1347): 4.52e-17: 89.6: 16.17