Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 23178491, unassigned3713
Identification Methods biochemical, tandem affinity purification, fluorescence polarization spectroscopy
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016605 - PML body
GO:0050821 - protein stabilization
GO:1901796 - regulation of signal transduction by p53 class mediator
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 543
Hs

1 1102
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024