Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Interactor 2: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.64 | 0.60 | 0.620 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17380128 |
| Identification Methods | enzymatic study, pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0016605 - PML body GO:0031625 - ubiquitin protein ligase binding and 1 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Mm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
