Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Interactor 2: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 23178491, 15380617
Identification Methods biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Pkinase, HEAT_2~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 543
Hs

1 589
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024