Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Interactor 2: AATF (Q9NY61)
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1)
Gene: AATF
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.63 | 0.55 | 0.589 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17157788 |
| Identification Methods | pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006974 - DNA damage response GO:0019901 - protein kinase binding |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
