HitPredict

Interactor 1: ACL6A (O96019)
Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)
Gene: ACTL6A

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0035267 - NuA4 histone acetyltransferase complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 429 Hs			1 375
+	Hs
		929902 ACTG_HUMAN (9-428): 0: 553: 34.29		POTEE_HUMAN (1-375): 0: 729: 91.47
+	Hs
		331479 ACL6A_HUMAN (1-429): 0: 597: 100.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		331489 ACL6A_HUMAN (1-429): 0: 597: 100.00		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Xl
		292756 Q7ZYI5_XENLA (1-429): 0: 587: 92.31		ACTB_XENLA (1-375): 0: 604: 98.93
+	Dm
		361129 ACT4_DROME (9-428): 0: 566: 35.48		ACT2_DROME (2-375): 0: 598: 97.59
+	Dm
		361164 ACT4_DROME (9-428): 0: 566: 35.48		ACT5_DROME (2-375): 0: 598: 95.46
+	Dm
		361177 ACT4_DROME (9-428): 0: 566: 35.48		ACT3_DROME (2-375): 0: 596: 94.92
+	Dm
		361179 ACT4_DROME (9-428): 0: 566: 35.48		ACT6_DROME (2-375): 0: 596: 95.46
+	Gg
		891646 ACTB_CHICK (9-428): 0: 553: 34.29		ACTB_CHICK (1-375): 0: 604: 98.93
+	Hs
		891648 ACTB_HUMAN (9-428): 0: 553: 34.29		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		891675 ACTG_HUMAN (9-428): 0: 553: 34.29		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		929815 ACTG_HUMAN (9-428): 0: 553: 34.29		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		929883 Q1KLZ0_HUMAN (9-428): 0: 553: 34.29		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		891680 ACTB_HUMAN (9-428): 0: 553: 34.29		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		929817 ACTG_HUMAN (9-428): 0: 553: 34.29		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		891666 ACTB_HUMAN (9-428): 0: 553: 34.29		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		891676 ACTB_HUMAN (9-428): 0: 553: 34.29		ACTH_HUMAN (2-375): 0: 592: 94.39
+	Hs
		929816 ACTG_HUMAN (9-428): 0: 553: 34.29		ACTH_HUMAN (2-375): 0: 592: 94.39