Protein: APOL2
Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II)

Gene: APOL2
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9BQE5

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005789 - endoplasmic reticulum membrane
GO:0006629 - lipid metabolic process
GO:0006869 - lipid transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1027926

PSG9
Pregnancy-specific beta-1-glycoprotein 9

3

1

High-throughput

0.861

High

507345

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

0

High-throughput

0.638

High

1369621

APBB2
Amyloid beta precursor protein binding family B member 2

3

0

High-throughput

0.638

High

733716

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

2

High-throughput

0.628

High

820732

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.618

High

932707

EMP1
Epithelial membrane protein 1

2

1

High-throughput

0.606

High

1159627

STX1A
Syntaxin-1A

2

2

High-throughput

0.606

High

1195265

TM52B
Transmembrane protein 52B

2

1

High-throughput

0.606

High

1410687

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

1

High-throughput

0.606

High

361345

SODC
Superoxide dismutase [Cu-Zn]

2

0

High-throughput

0.602

High

1399907

GBP5
Guanylate-binding protein 5

2

0

High-throughput

0.602

High

1410681

ERAP1
Endoplasmic reticulum aminopeptidase 1

2

0

High-throughput

0.602

High

1410679

CC50A
Cell cycle control protein 50A

2

0

High-throughput

0.585

High

129893

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.580

High

166993

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.580

High

424099

ITB2
Integrin beta-2

2

0

High-throughput

0.580

High

926834

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.580

High

933985

APOC4
Apolipoprotein C-IV

2

0

High-throughput

0.580

High

1067222

KCNA1
Potassium voltage-gated channel subfamily A member 1

2

0

High-throughput

0.580

High

1308345

TM139
Transmembrane protein 139

2

0

High-throughput

0.580

High

1327944

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.580

High

1401212

PANX1
Pannexin-1

2

0

High-throughput

0.580

High

1410430

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.580

High

1410668

S26A6
Solute carrier family 26 member 6

2

0

High-throughput

0.580

High

1410673

TMM60
Transmembrane protein 60

2

0

High-throughput

0.580

High

1410680

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

1410682

USE1
Vesicle transport protein USE1

2

0

High-throughput

0.580

High

855380

5HT3A
5-hydroxytryptamine receptor 3A

2

3

High-throughput

0.574

High

1057577

ACHD
Acetylcholine receptor subunit delta

2

2

High-throughput

0.574

High

951383

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

335261

CXB5
Gap junction beta-5 protein

2

5

High-throughput

0.553

High

746219

STX2
Syntaxin-2

2

2

High-throughput

0.553

High

1207594

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

543275

UBL4A
Ubiquitin-like protein 4A

1

1

High-throughput

0.536

High

774582

BASI
Basigin

1

1

High-throughput

0.536

High

840603

DPP6
A-type potassium channel modulatory protein DPP6

1

1

High-throughput

0.536

High

380476

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

0

High-throughput

0.513

High

1349971

CERK1
Ceramide kinase

1

0

High-throughput

0.513

High

1350592

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.513

High

1396507

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.513

High

1402815

TM209
Transmembrane protein 209

1

0

High-throughput

0.493

High

539740

ACHB
Acetylcholine receptor subunit beta

1

2

High-throughput

0.489

High

1287283

DPP9
Dipeptidyl peptidase 9

1

1

High-throughput

0.489

High

1410689

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

1410669

ELOV4
Very long chain fatty acid elongase 4

1

1

High-throughput

0.481

High

1381501

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1410683

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.479

High

1410690

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

387633

APOC2
Apolipoprotein C-II

1

0

High-throughput

0.460

High

1396395

F210B
Protein FAM210B, mitochondrial

1

0

High-throughput

0.460

High

174069

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

333160

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

Small-scale

0.458

High

417710

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418392

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

537800

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

848067

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.458

High

904093

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1246955

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1366540

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1410667

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1410672

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1410686

XCT
Cystine/glutamate transporter

1

1

High-throughput

0.445

High

1410675

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

1

High-throughput

0.439

High

1410676

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.439

High

1238795

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1322967

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

1392442

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

564288

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1253164

NBEL2
Neurobeachin-like protein 2

1

0

High-throughput

0.426

High

1410671

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

349703

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

0

High-throughput

0.328

High

618482

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

2

0

High-throughput

0.318

High

1322862

EID3
EP300-interacting inhibitor of differentiation 3

2

0

High-throughput

0.318

High

139972

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

1245845

TMED8
Protein TMED8

2

0

High-throughput

0.316

High

1288123

MARH3
E3 ubiquitin-protein ligase MARCHF3

2

0

High-throughput

0.316

High

1350630

SFXN5
Sideroflexin-5

2

0

High-throughput

0.316

High

1361957

BSND
Barttin

2

0

High-throughput

0.316

High

1383962

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

1388795

YIPF6
Protein YIPF6

2

0

High-throughput

0.316

High

1410670

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

1410688

SIT1
Signaling threshold-regulating transmembrane adapter 1

2

0

High-throughput

0.316

High

67382

RTL8C
Retrotransposon Gag-like protein 8C

1

0

High-throughput

0.279

Low

245265

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

0

High-throughput

0.279

Low

691833

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.279

Low

867672

GPR12
G-protein coupled receptor 12

1

0

High-throughput

0.279

Low

880192

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

1012950

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.279

Low

1066762

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.279

Low

1212293

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.279

Low

1410674

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.279

Low

1410677

ANM8
Protein arginine N-methyltransferase 8

1

0

High-throughput

0.279

Low

1410684

POLK
DNA polymerase kappa

1

0

High-throughput

0.279

Low

729110

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

0

High-throughput

0.269

Low

1281758

T179B
Transmembrane protein 179B

1

0

High-throughput

0.268

Low

386156

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

218689

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

294247

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

715743

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

831319

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

901009

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.249

Low

959041

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

1155708

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1410678

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.249

Low

1410685

UBQL2
Ubiquilin-2

1

0

High-throughput

0.249

Low

231627

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.232

Low

1177186

MICB
MHC class I polypeptide-related sequence B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025