Interactor 1: O96296 (O96296)
Erythrocyte membrane protein 1, PfEMP1
Gene: PF3D7_0223500

Interactor 2: Q8I2E3 (Q8I2E3)
Erythrocyte membrane protein 1, PfEMP1
Gene: PF3D7_0937800

Species: Plasmodium falciparum 3D7

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 16267556
Identification Methods two hybrid pooling approach
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CIDR1_gamma~PFEMP, Duffy_binding~Duffy_binding, Duffy_binding~NTS, Duffy_binding~PFEMP
Common GO terms GO:0016020 - membrane
GO:0020002 - host cell plasma membrane
GO:0020013 - modulation by symbiont of host erythrocyte aggregation
GO:0020030 - infected host cell surface knob
GO:0020033 - antigenic variation
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2177
Pf

1 2264
+ Pf
+ Pf

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Last updated: 15 Jul 2024