HitPredict

Interactor 1: LDHA (P00338)
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59)
Gene: LDHA

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35063084, 26269332
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 758
+	Hs
		421952 LDHB_HUMAN (1-331): 9.03e-153: 433: 75.30		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581942 LDHB_RAT (1-331): 2.76e-152: 432: 74.40		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94166 LDHB_RAT (1-331): 2.76e-152: 432: 74.40		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		496482 MDHM_HUMAN (1-332): 1.4e-108: 321: 19.19		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496481 MDHC_HUMAN (22-332): 6.85e-107: 317: 21.23		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00