Interactor 1: DHE3 (P00367)
Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)
Gene: GLUD1

Interactor 2: SIR3 (Q9NTG7)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)
Gene: SIRT3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 31108370
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0032024 - positive regulation of insulin secretion
GO:0070403 - NAD+ binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 558
Hs

1 399
+ Hs
+ Mm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024