Protein: RTRAF
RNA transcription, translation and transport factor protein (CLE7 homolog) (CLE) (hCLE)

Gene: RTRAF
Organism: Homo sapiens
Interactions: 202
UniProt ID: Q9Y224

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1490441

RTRAF
RNA transcription, translation and transport factor protein

2

0

Small-scale

0.797

High

1335334

FA98A
Protein FAM98A

11

2

Small-scale

0.754

High

1198093

FA98B
Protein FAM98B

8

3

Small-scale

0.742

High

1363359

DDX1
ATP-dependent RNA helicase DDX1

7

1

Small-scale

0.741

High

1490443

RTCB
RNA-splicing ligase RtcB homolog

9

0

Small-scale

0.718

High

1114682

CUL3
Cullin-3

2

4

High-throughput

0.611

High

1415180

ASHWN
Ashwin

2

0

High-throughput

0.595

High

766024

BMI1
Polycomb complex protein BMI-1

2

0

High-throughput

0.585

High

1116145

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

0

High-throughput

0.585

High

243314

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

373525

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

530605

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.576

High

397247

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

775379

FUS
RNA-binding protein FUS

2

1

High-throughput

0.571

High

1165415

FA98C
Protein FAM98C

2

3

Small-scale

0.571

High

1430098

RGAP1
Rac GTPase-activating protein 1

2

2

High-throughput

0.571

High

1448575

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.565

High

272558

OBSL1
Obscurin-like protein 1

2

0

High-throughput

0.559

High

590057

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.559

High

696890

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

769539

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.559

High

1271912

MEPCE
7SK snRNA methylphosphate capping enzyme

2

0

High-throughput

0.559

High

340267

PCNT
Pericentrin

1

1

High-throughput

0.541

High

857600

NOTC1
Neurogenic locus notch homolog protein 1

1

2

High-throughput

0.536

High

1027857

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

1112800

CUL1
Cullin-1

1

4

High-throughput

0.536

High

1113030

CUL2
Cullin-2

1

4

High-throughput

0.536

High

1115489

CUL4B
Cullin-4B

1

4

High-throughput

0.536

High

1160806

DREB
Drebrin

1

1

High-throughput

0.536

High

1370474

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.536

High

1371899

CUL5
Cullin-5

1

4

High-throughput

0.536

High

1415648

RIOK2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.536

High

1462231

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.536

High

1326392

NIN
Ninein

1

0

Small-scale

0.529

High

135734

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.513

High

141172

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

245293

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

0

High-throughput

0.513

High

361382

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

484684

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

564575

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

694074

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

846534

MATR3
Matrin-3

1

0

High-throughput

0.513

High

867523

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

926246

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.513

High

970176

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

1119040

BYST
Bystin

1

0

High-throughput

0.513

High

1270674

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

1291287

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1360531

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1390998

THOC1
THO complex subunit 1

1

0

High-throughput

0.513

High

1391976

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

1490445

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

132385

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

135392

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

1

High-throughput

0.479

High

260623

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

335202

ARI2
E3 ubiquitin-protein ligase ARIH2

1

1

High-throughput

0.479

High

406810

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

520464

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

587537

TFE2
Transcription factor E2-alpha

1

1

High-throughput

0.479

High

607232

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

790113

ZEB1
Zinc finger E-box-binding homeobox 1

1

1

Small-scale

0.479

High

851823

NKX21
Homeobox protein Nkx-2.1

1

1

High-throughput

0.479

High

900562

FXR2
RNA-binding protein FXR2

1

1

High-throughput

0.479

High

965337

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

1024938

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1040944

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

1087700

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

1

High-throughput

0.479

High

1092274

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

1101103

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

1198151

RHG29
Rho GTPase-activating protein 29

1

3

High-throughput

0.479

High

1253250

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

2

High-throughput

0.479

High

1256139

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1260641

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.479

High

1280610

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

1280777

YTHD3
YTH domain-containing family protein 3

1

1

High-throughput

0.479

High

1291786

ARHGP
Rho guanine nucleotide exchange factor 25

1

1

High-throughput

0.479

High

1347897

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

1367615

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1380261

FBXW7
F-box/WD repeat-containing protein 7

1

2

Small-scale

0.479

High

1387862

ZBT10
Zinc finger and BTB domain-containing protein 10

1

1

Small-scale

0.479

High

1399589

ARHGH
Rho guanine nucleotide exchange factor 17

1

1

High-throughput

0.479

High

1411761

RIOK1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

1418843

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

High-throughput

0.479

High

1420384

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

High-throughput

0.479

High

1421205

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.479

High

1436828

WDR76
WD repeat-containing protein 76

1

2

High-throughput

0.479

High

1437887

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

High-throughput

0.479

High

1446447

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1449007

RHG35
Rho GTPase-activating protein 35

1

1

High-throughput

0.479

High

1490442

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.479

High

1490446

YTHD2
YTH domain-containing family protein 2

1

1

High-throughput

0.479

High

74071

MYO9A
Unconventional myosin-IXa

1

0

High-throughput

0.458

High

125666

LEG9
Galectin-9

1

0

High-throughput

0.458

High

129567

MEN1
Menin

1

0

High-throughput

0.458

High

131535

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

Small-scale

0.458

High

158000

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

227711

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

294538

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

316172

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

320152

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

325167

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

348001

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

350182

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

386372

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

401716

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

485521

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

584597

VAV
Proto-oncogene vav

1

0

High-throughput

0.458

High

596432

H12
Histone H1.2

1

0

High-throughput

0.458

High

630095

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

660755

IF4B
Eukaryotic translation initiation factor 4B

1

0

Small-scale

0.458

High

667518

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

713874

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

0

High-throughput

0.458

High

731709

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

766951

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

831666

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

837907

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

879625

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

888400

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

898546

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

927177

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

947317

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

959298

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

971302

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

980558

H4
Histone H4

1

0

High-throughput

0.458

High

990884

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

995904

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1022204

DAB2
Disabled homolog 2

1

0

Small-scale

0.458

High

1036001

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1067852

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1088622

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.458

High

1096658

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

1107342

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1121375

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1122201

UBP2L
Ubiquitin-associated protein 2-like

1

0

High-throughput

0.458

High

1127253

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

1138766

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1141055

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1165530

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

0

High-throughput

0.458

High

1187093

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

1276984

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1277969

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1290828

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1313541

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1323590

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.458

High

1332919

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.458

High

1339765

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1352843

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1364706

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1385924

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1393834

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1397567

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1399867

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1405579

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1406524

ATX2
Ataxin-2

1

0

High-throughput

0.458

High

1407956

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1415913

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1421014

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1429889

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1434258

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1435711

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1438086

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

1438949

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.458

High

1447455

ANLN
Anillin

1

0

High-throughput

0.458

High

1449253

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1451320

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1459343

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1490444

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

Small-scale

0.458

High

430523

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

587259

ITF2
Transcription factor 4

1

1

Small-scale

0.445

High

1057056

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.445

High

1063205

GOGA3
Golgin subfamily A member 3

1

1

Small-scale

0.445

High

1253181

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.445

High

1368916

RBP56
TATA-binding protein-associated factor 2N

1

1

Small-scale

0.445

High

1405541

ZBT18
Zinc finger and BTB domain-containing protein 18

1

1

High-throughput

0.445

High

1450509

DJC11
DnaJ homolog subfamily C member 11

1

1

Small-scale

0.445

High

869807

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.439

High

1458522

TRPC4
Short transient receptor potential channel 4

1

1

High-throughput

0.437

High

1461706

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

274811

DNJB6
DnaJ homolog subfamily B member 6

1

0

Small-scale

0.426

High

354805

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

701938

ABCD3
ATP-binding cassette sub-family D member 3

1

0

Small-scale

0.426

High

904202

BAP31
B-cell receptor-associated protein 31

1

0

Small-scale

0.426

High

909252

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.426

High

952385

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.426

High

987270

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

Small-scale

0.426

High

1119375

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1326154

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1416435

SSBP3
Single-stranded DNA-binding protein 3

1

0

Small-scale

0.426

High

1430645

CCDC8
Coiled-coil domain-containing protein 8

1

0

Small-scale

0.426

High

1431204

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

0

Small-scale

0.426

High

1437413

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

887348

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

1257237

NEK10
Serine/threonine-protein kinase Nek10

1

1

High-throughput

0.407

High

1460376

PS1C2
Psoriasis susceptibility 1 candidate gene 2 protein

2

0

High-throughput

0.316

High

846110

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.288

High

389570

FINC
Fibronectin

1

0

High-throughput

0.279

Low

412828

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1126213

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1348253

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1418528

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1446690

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025