HitPredict

Interactor 1: COX1 (P00401)
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)
Gene: COX1

Interactor 2: COX4 (P04037)
Cytochrome c oxidase subunit 4, mitochondrial (Cytochrome c oxidase polypeptide IV)
Gene: COX4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.953

Property	Details
Experiments	28821616, 23864706, 27083394, 24478450, 29386296, 37968396, 22342701
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	COX1~COX5B
Common GO terms	GO:0005739 - mitochondrion GO:0005751 - mitochondrial respiratory chain complex IV GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 534 Sc			1 155
+	Sc
		373317 SCE4_YEAST (1-324): 6.65e-167: 488: 100.00		COX4_YEAST (1-155): 7.72e-80: 234: 100.00
+	Sc
		371050 SCE2_YEAST (1-249): 1.49e-116: 357: 96.79		COX4_YEAST (1-155): 7.72e-80: 234: 100.00
+	Sc
		371045 SCE3_YEAST (1-81): 8.18e-32: 128: 100.00		COX4_YEAST (1-155): 7.72e-80: 234: 100.00
+	Sc
		371040 AI2M_YEAST (1-113): 1.35e-24: 110: 66.67		COX4_YEAST (1-155): 7.72e-80: 234: 100.00