HitPredict

Interactor 1: SODC (P00441)
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1)
Gene: SOD1

Interactor 2: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29128334, 24981860
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 154 Hs			1 645
+	Dm
		870420 SODC_DROME (1-154): 8.71e-66: 199: 61.04		PDI_DROME (53-504): 1.95e-49: 181: 20.13
+	Hs
		336308 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11
+	Rn
		388064 SODC_RAT (1-154): 7.24e-71: 211: 83.12		PDIA1_RAT (4-197): 4.14e-32: 132: 25.25
+	Hs
		336499 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51
+	Hs
		336381 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35