HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

The method score is based on:

Property	Details
Experiments	18619508, 19818398
Identification Methods	enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, in-gel kinase assay
Interaction Type	direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0034976 - response to endoplasmic reticulum stress GO:0043065 - positive regulation of apoptotic process and 3 others more... GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051726 - regulation of cell cycle GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	1130
Hs

1	331

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024