HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15937340, 16723087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 840
+	Hs
		522818 SRC_HUMAN (13-510): 0: 547: 38.58		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		412053 FYN_HUMAN (18-510): 0: 543: 38.64		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		523090 SRC_HUMAN (13-510): 0: 547: 38.58		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		412286 FYN_HUMAN (18-510): 0: 543: 38.64		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		714124 CSK_HUMAN (61-500): 1.81e-155: 472: 37.72		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		782813 CSK_HUMAN (61-500): 1.81e-155: 472: 37.72		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		337324 ABL1_HUMAN (1-1130): 0: 984: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		503608 ABL2_HUMAN (10-1130): 0: 775: 52.62		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		503340 SRC_HUMAN (13-510): 0: 547: 38.58		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		411965 FYN_HUMAN (18-510): 0: 543: 38.64		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		433227 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		411570 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		442767 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		411586 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		442775 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		503596 CSK_HUMAN (61-500): 1.81e-155: 472: 37.72		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		564025 CSK_HUMAN (61-500): 1.81e-155: 472: 37.72		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86