HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19380743, 17474147
Identification Methods	affinity chromatography technology, peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0017124 - SH3 domain binding GO:0098794 - postsynapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 896
+	Hs
		69204 A9UF07_HUMAN (25-1130): 0: 945: 99.73		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		337577 ABL1_HUMAN (1-1130): 0: 984: 100.00		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Hs
		412069 FYN_HUMAN (18-510): 0: 543: 38.64		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Ce
		371330 ABL1_CAEEL (3-1130): 0: 606: 32.11		Q9BIF4_CAEEL (7-213): 5.25e-19: 94.5: 37.55
+	Hs
		411908 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72
+	Hs
		434101 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72
+	Hs
		433781 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Ce
		106690 SRC1_CAEEL (9-508): 5.12e-160: 487: 36.52		Q9BIF4_CAEEL (7-213): 5.25e-19: 94.5: 37.55