HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: ADA15 (Q13444)
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)
Gene: ADAM15

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11741929
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007229 - integrin-mediated signaling pathway GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 863
+	Hs
		152218 ABL1_HUMAN (1-1130): 0: 984: 100.00		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		522964 SRC_HUMAN (13-510): 0: 547: 38.58		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		412180 FYN_HUMAN (18-510): 0: 543: 38.64		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		433344 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		411708 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		442824 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		197583 SRC_HUMAN (13-510): 0: 547: 38.58		ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32
+	Hs
		197579 FYN_HUMAN (18-510): 0: 543: 38.64		ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32
+	Hs
		523142 SRC_HUMAN (13-510): 0: 547: 38.58		ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00
+	Hs
		522899 SRC_HUMAN (13-510): 0: 547: 38.58		ADAM8_HUMAN (1-851): 5.57e-160: 489: 31.26
+	Hs
		197581 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32
+	Hs
		442882 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00
+	Hs
		197580 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32
+	Hs
		442890 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		ADA22_HUMAN (7-698): 1.49e-136: 430: 27.98
+	Hs
		152242 SRC_HUMAN (13-510): 0: 547: 38.58		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152228 FYN_HUMAN (18-510): 0: 543: 38.64		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152229 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152227 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152233 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		522906 SRC_HUMAN (13-510): 0: 547: 38.58		ADA17_HUMAN (348-534): 2.91e-20: 98.6: 32.29