Protein: PSD10
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))

Gene: PSD10, PSMD10
Organism: Homo sapiens
Interactions: 113
UniProt ID: O75832

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000502 - proteasome complex
GO:0003950 - NAD+ ADP-ribosyltransferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276152

PRS6B
26S proteasome regulatory subunit 6B

14

8

Small-scale

0.989

High

276164

PRS8
26S proteasome regulatory subunit 8

6

9

Small-scale

0.953

High

276163

PRS4
26S proteasome regulatory subunit 4

6

8

Small-scale

0.947

High

276147

PRS7
26S proteasome regulatory subunit 7

6

7

Small-scale

0.943

High

276139

PRS6A
26S proteasome regulatory subunit 6A

5

13

Small-scale

0.922

High

276166

PRS10
26S proteasome regulatory subunit 10B

4

10

Small-scale

0.896

High

276137

CDK4
Cyclin-dependent kinase 4

2

5

Small-scale

0.821

High

276172

TF65
Transcription factor p65

2

7

Small-scale

0.806

High

276216

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

2

19

Small-scale

0.806

High

130667

PSDE
26S proteasome non-ATPase regulatory subunit 14

8

9

Small-scale

0.748

High

121901

PSD12
26S proteasome non-ATPase regulatory subunit 12

7

3

Small-scale

0.747

High

276222

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

7

14

Small-scale

0.746

High

208966

NCK2
Cytoplasmic protein NCK2

1

18

Small-scale

0.724

High

276140

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

16

Small-scale

0.724

High

276156

PSMD7
26S proteasome non-ATPase regulatory subunit 7

5

6

High-throughput

0.718

High

276160

PSMD4
26S proteasome non-ATPase regulatory subunit 4

5

2

Small-scale

0.716

High

276171

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

8

Small-scale

0.715

High

121646

PSD11
26S proteasome non-ATPase regulatory subunit 11

4

3

Small-scale

0.694

High

276182

PSMD6
26S proteasome non-ATPase regulatory subunit 6

4

4

Small-scale

0.694

High

276205

PSMD1
26S proteasome non-ATPase regulatory subunit 1

4

4

Small-scale

0.694

High

276209

PAAF1
Proteasomal ATPase-associated factor 1

4

13

Small-scale

0.694

High

276184

ADRM1
Proteasomal ubiquitin receptor ADRM1

4

1

High-throughput

0.694

High

276131

RB
Retinoblastoma-associated protein

4

2

Small-scale

0.686

High

276169

MDM2
E3 ubiquitin-protein ligase Mdm2

3

3

Small-scale

0.680

High

198504

PSMD3
26S proteasome non-ATPase regulatory subunit 3

3

2

High-throughput

0.671

High

276176

PSMD2
26S proteasome non-ATPase regulatory subunit 2

3

4

High-throughput

0.671

High

276138

PTN2
Tyrosine-protein phosphatase non-receptor type 2

3

10

High-throughput

0.667

High

276195

LDB1
LIM domain-binding protein 1

1

0

High-throughput

0.663

High

276220

PSD13
26S proteasome non-ATPase regulatory subunit 13

3

2

Small-scale

0.662

High

276173

UBE3A
Ubiquitin-protein ligase E3A

3

14

Small-scale

0.656

High

276158

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

3

4

Small-scale

0.650

High

226081

PRKN
E3 ubiquitin-protein ligase parkin

3

9

Small-scale

0.640

High

276188

CCD92
Coiled-coil domain-containing protein 92

3

0

High-throughput

0.638

High

276154

PSMD8
26S proteasome non-ATPase regulatory subunit 8

2

1

High-throughput

0.628

High

276130

P53
Cellular tumor antigen p53

1

9

Small-scale

0.618

High

276162

RHOA
Transforming protein RhoA

1

20

Small-scale

0.618

High

276177

DUS8
Dual specificity protein phosphatase 8

1

8

High-throughput

0.618

High

276192

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

276208

DUS9
Dual specificity protein phosphatase 9

1

7

High-throughput

0.618

High

276219

DUS12
Dual specificity protein phosphatase 12

1

8

High-throughput

0.618

High

276204

CC74B
Coiled-coil domain-containing protein 74B

3

1

High-throughput

0.609

High

276185

PSMD5
26S proteasome non-ATPase regulatory subunit 5

2

0

High-throughput

0.602

High

276161

SEM1
26S proteasome complex subunit SEM1

3

0

Small-scale

0.597

High

124542

CLIC1
Chloride intracellular channel protein 1

1

1

Small-scale

0.597

High

276175

GRSF1
G-rich sequence factor 1

1

3

Small-scale

0.597

High

276134

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

7

High-throughput

0.595

High

276151

MAGA4
Melanoma-associated antigen 4

1

11

Small-scale

0.586

High

276174

EP300
Histone acetyltransferase p300

2

13

Small-scale

0.584

High

276190

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.575

High

276155

CEBPA
CCAAT/enhancer-binding protein alpha

2

6

Small-scale

0.563

High

276135

HS71A
Heat shock 70 kDa protein 1A

1

12

Small-scale

0.561

High

276146

HSP74
Heat shock 70 kDa protein 4

1

16

Small-scale

0.561

High

276145

AGTR1
Type-1 angiotensin II receptor

1

5

High-throughput

0.541

High

122126

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

2

High-throughput

0.536

High

152756

RGPD8
RANBP2-like and GRIP domain-containing protein 8

1

6

High-throughput

0.536

High

276129

HERC2
E3 ubiquitin-protein ligase HERC2

1

13

High-throughput

0.536

High

276136

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.536

High

276206

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

6

High-throughput

0.536

High

276207

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.536

High

276218

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

High-throughput

0.536

High

276125

DDAH1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

1

0

Small-scale

0.530

High

276223

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.518

High

235028

DOK2
Docking protein 2

1

5

High-throughput

0.515

High

276167

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.515

High

276133

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

276215

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

276144

CCND2
G1/S-specific cyclin-D2

1

2

Small-scale

0.501

High

276202

CC74A
Coiled-coil domain-containing protein 74A

1

1

High-throughput

0.489

High

125054

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

Small-scale

0.479

High

262337

TULP3
Tubby-related protein 3

1

2

High-throughput

0.479

High

276127

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

276128

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

2

Small-scale

0.479

High

276132

HS90A
Heat shock protein HSP 90-alpha

1

16

Small-scale

0.479

High

276141

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

276148

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

276149

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

Small-scale

0.479

High

276153

YAP1
Transcriptional coactivator YAP1

1

18

Small-scale

0.479

High

276157

GDIR1
Rho GDP-dissociation inhibitor 1

1

2

Small-scale

0.479

High

276159

RD23B
UV excision repair protein RAD23 homolog B

1

4

High-throughput

0.479

High

276165

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.479

High

276170

PO5F1
POU domain, class 5, transcription factor 1

1

7

Small-scale

0.479

High

276178

CUL3
Cullin-3

1

18

High-throughput

0.479

High

276179

TRI14
Tripartite motif-containing protein 14

1

12

High-throughput

0.479

High

276180

KEAP1
Kelch-like ECH-associated protein 1

1

1

Small-scale

0.479

High

276181

BECN1
Beclin-1

1

1

Small-scale

0.479

High

276186

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.479

High

276187

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

276191

DDI2
Protein DDI1 homolog 2

1

4

High-throughput

0.479

High

276194

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

13

High-throughput

0.479

High

276196

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

276197

ZFN2B
AN1-type zinc finger protein 2B

1

1

High-throughput

0.479

High

276198

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

2

Small-scale

0.479

High

276199

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

14

High-throughput

0.479

High

276200

CBP
CREB-binding protein

1

11

Small-scale

0.479

High

276201

CELF1
CUGBP Elav-like family member 1

1

6

Small-scale

0.479

High

276212

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

13

Small-scale

0.479

High

276214

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

276217

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

276221

RNF11
RING finger protein 11

1

3

Small-scale

0.479

High

276126

ATG12
Ubiquitin-like protein ATG12

1

0

Small-scale

0.458

High

276142

NFYA
Nuclear transcription factor Y subunit alpha

1

0

Small-scale

0.458

High

276143

NFYB
Nuclear transcription factor Y subunit beta

1

0

Small-scale

0.458

High

276168

HSF1
Heat shock factor protein 1

1

0

Small-scale

0.458

High

276193

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.458

High

276203

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

0

Small-scale

0.458

High

276213

ATG5
Autophagy protein 5

1

0

Small-scale

0.458

High

681

A0A087WW66
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.445

High

56580

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

2

High-throughput

0.445

High

276150

CNDD3
Condensin-2 complex subunit D3

1

2

High-throughput

0.445

High

276183

ABRX2
BRISC complex subunit Abraxas 2

1

1

Small-scale

0.445

High

276211

ZDHC5
Palmitoyltransferase ZDHHC5

1

5

High-throughput

0.445

High

276189

TMM31
Transmembrane protein 31

1

0

High-throughput

0.279

Low

276210

ELOV1
Very long chain fatty acid elongase 1

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024