Protein: PSMG1
Proteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2) (Proteasome chaperone homolog 1) (Pba1)

Gene: PSMG1
Organism: Homo sapiens
Interactions: 91
UniProt ID: O95456

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

337442

PSA1
Proteasome subunit alpha type-1

9

4

High-throughput

0.970

High

337485

PSMG2
Proteasome assembly chaperone 2

10

0

Small-scale

0.926

High

337490

PSB7
Proteasome subunit beta type-7

5

4

High-throughput

0.925

High

337447

PSB9
Proteasome subunit beta type-9

4

6

High-throughput

0.903

High

337443

PSA2
Proteasome subunit alpha type-2

4

5

Small-scale

0.895

High

337448

PSA5
Proteasome subunit alpha type-5

4

4

Small-scale

0.892

High

337440

PSB1
Proteasome subunit beta type-1

3

7

High-throughput

0.871

High

337457

PSB3
Proteasome subunit beta type-3

3

5

High-throughput

0.871

High

337458

PSB2
Proteasome subunit beta type-2

3

5

High-throughput

0.871

High

165224

PSA7
Proteasome subunit alpha type-7

3

4

Small-scale

0.861

High

337462

PSA6
Proteasome subunit alpha type-6

3

5

Small-scale

0.847

High

337449

PSB4
Proteasome subunit beta type-4

2

6

High-throughput

0.811

High

337444

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.691

High

337445

PSA4
Proteasome subunit alpha type-4

1

5

High-throughput

0.691

High

337450

PSB6
Proteasome subunit beta type-6

1

6

High-throughput

0.691

High

337500

POMP
Proteasome maturation protein

3

0

Small-scale

0.628

High

337451

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

1

High-throughput

0.606

High

337477

FOXR2
Forkhead box protein R2

2

0

High-throughput

0.602

High

337494

PSMG3
Proteasome assembly chaperone 3

2

0

Small-scale

0.585

High

259259

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

114578

H0YKT8
Proteasome subunit beta

1

5

High-throughput

0.575

High

337434

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

1

High-throughput

0.541

High

127848

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

1

High-throughput

0.536

High

337454

PRS6B
26S proteasome regulatory subunit 6B

1

2

High-throughput

0.536

High

337463

PRS4
26S proteasome regulatory subunit 4

1

2

High-throughput

0.536

High

337464

PRS8
26S proteasome regulatory subunit 8

1

2

High-throughput

0.536

High

337471

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.536

High

286132

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.518

High

337431

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.518

High

337455

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.518

High

337468

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.518

High

177639

SMAD7
Mothers against decapentaplegic homolog 7

1

0

High-throughput

0.513

High

210823

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.513

High

337429

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.513

High

337439

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

337460

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.513

High

337461

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.513

High

337467

CUL1
Cullin-1

1

0

High-throughput

0.513

High

337470

PSME4
Proteasome activator complex subunit 4

1

0

High-throughput

0.513

High

337473

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

0

High-throughput

0.513

High

337474

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

High-throughput

0.513

High

337475

PSMG4
Proteasome assembly chaperone 4

1

0

High-throughput

0.513

High

337480

LRA25
Leucine repeat adapter protein 25

1

0

High-throughput

0.513

High

337483

PSMF1
Proteasome inhibitor PI31 subunit

1

0

High-throughput

0.513

High

337487

AURKB
Aurora kinase B

1

0

High-throughput

0.513

High

337492

SOST
Sclerostin

1

0

High-throughput

0.513

High

337497

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.513

High

337498

DONS
Protein downstream neighbor of Son

1

0

High-throughput

0.513

High

337502

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

High-throughput

0.513

High

337435

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.493

High

337453

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.481

High

337476

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.480

High

337437

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.479

High

337441

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

337472

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

337491

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

1

High-throughput

0.479

High

217662

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

240378

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

324071

CE152
Centrosomal protein of 152 kDa

1

0

High-throughput

0.458

High

337426

PSMG1
Proteasome assembly chaperone 1

1

0

Small-scale

0.458

High

337427

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

337430

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

337432

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

337436

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

337446

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

337452

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

337459

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

337465

PPARD
Peroxisome proliferator-activated receptor delta

1

0

Small-scale

0.458

High

337466

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

337469

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

337479

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

337481

CE120
Centrosomal protein of 120 kDa

1

0

High-throughput

0.458

High

337484

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

337488

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

337499

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

298132

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.426

High

337433

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

337438

IL1RA
Interleukin-1 receptor antagonist protein

1

0

High-throughput

0.426

High

337501

FBX7
F-box only protein 7

1

0

High-throughput

0.426

High

681

A0A087WW66
26S proteasome non-ATPase regulatory subunit 1

1

1

High-throughput

0.407

High

97057

E9PMD8
Proteasome 26S subunit, ATPase 3

1

3

High-throughput

0.407

High

337456

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

337496

CAH10
Carbonic anhydrase-related protein 10

4

0

High-throughput

0.360

High

337478

SPAT8
Spermatogenesis-associated protein 8

2

0

High-throughput

0.328

High

337482

XAGE3
X antigen family member 3

2

0

High-throughput

0.328

High

337493

PHAF1
Phagosome assembly factor 1

2

0

High-throughput

0.313

High

337489

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.282

High

337428

FINC
Fibronectin

1

0

High-throughput

0.279

Low

337495

NRIP3
Nuclear receptor-interacting protein 3

1

0

High-throughput

0.279

Low

337486

RHDF1
Inactive rhomboid protein 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025