HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: PHAG1 (Q9NWQ8)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp)
Gene: PAG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	9334312
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	GO:0042169 - SH2 domain binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 432
+	Hs
		523175 SRC_HUMAN (13-510): 0: 547: 38.58		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		763390 FYN_MOUSE (18-510): 0: 542: 38.64		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		412375 FYN_HUMAN (18-510): 0: 543: 38.64		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		411925 LCK_MOUSE (9-508): 5.49e-179: 535: 38.30		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		411873 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Hs
		789135 FRK_HUMAN (31-511): 1.18e-176: 529: 39.80		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		976830 ITK_MOUSE (44-496): 8.69e-171: 518: 36.23		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Mm
		639443 LYN_MOUSE (9-508): 4.68e-172: 517: 35.77		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		434038 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		782848 CSK_MOUSE (61-500): 2.58e-155: 472: 37.95		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		782829 CSK_HUMAN (61-500): 1.81e-155: 472: 37.72		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Rn
		693647 CSK_RAT (61-500): 1.79e-155: 472: 37.72		PHAG1_RAT (1-432): 0: 740: 79.13