HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: GPR45 (Q9Y5Y3)
Probable G-protein coupled receptor 45 (PSP24-1) (PSP24-alpha)
Gene: GPR45

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 372
+	Hs
		337368 ABL1_HUMAN (1-1130): 0: 984: 100.00		GASR_HUMAN (24-337): 4.55e-18: 87: 26.36
+	Hs
		428898 SRC_HUMAN (13-510): 0: 547: 38.58		ADRB2_HUMAN (2-347): 3.64e-79: 250: 22.03
+	Hs
		412428 FYN_HUMAN (18-510): 0: 543: 38.64		GPR45_HUMAN (1-372): 8.07e-78: 245: 100.00
+	Mm
		403428 SRC_MOUSE (13-510): 0: 545: 38.19		5HT4R_MOUSE (20-368): 4.06e-70: 226: 22.16
+	Rn
		706745 SRC_RAT (13-510): 0: 549: 38.11		OPRM_RAT (3-370): 3.82e-66: 216: 16.27
+	Mm
		403417 SRC_MOUSE (13-510): 0: 545: 38.19		SSR3_MOUSE (2-357): 3.3e-66: 217: 22.35
+	Mm
		677190 FYN_MOUSE (18-510): 0: 542: 38.64		SSR3_MOUSE (2-357): 3.3e-66: 217: 22.35
+	Hs
		412346 FYN_HUMAN (18-510): 0: 543: 38.64		GPR63_HUMAN (11-372): 2.9e-65: 214: 52.49
+	Mm
		677255 YES_MOUSE (9-510): 4.7e-178: 534: 38.21		SSR3_MOUSE (2-357): 3.3e-66: 217: 22.35
+	Hs
		433596 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		5HT2A_HUMAN (3-367): 8.59e-66: 217: 18.83
+	Hs
		412050 FYN_HUMAN (18-510): 0: 543: 38.64		GASR_HUMAN (24-337): 4.55e-18: 87: 26.36
+	Hs
		412089 FYN_HUMAN (18-510): 0: 543: 38.64		5HT6R_HUMAN (51-340): 1.09e-17: 85.9: 26.49
+	Mm
		70552 B2RQ57_MOUSE (561-1130): 1.96e-54: 209: 22.36		SSR3_MOUSE (2-357): 3.3e-66: 217: 22.35