HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: AT1A1 (P05023)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: ATP1A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 35681168, 28065597, 16799092, 24797263
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0016323 - basolateral plasma membrane
GO:0016324 - apical plasma membrane
and 2 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 1023
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

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Last updated: 15 Jul 2024