HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: 4F2 (P08195)
Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
Gene: SLC3A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 24797263, 24189400, 16799092, 15657067
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001618 - virus receptor activity
GO:0005886 - plasma membrane
GO:0009925 - basal plasma membrane
GO:0009986 - cell surface
GO:0016020 - membrane
and 3 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 630
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024