Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: PPM1A (P35813)
Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA)
Gene: PPM1A
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 0.60 | 0.582 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28065597 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, ubiquitin reconstruction |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045893 - positive regulation of DNA-templated transcription GO:0090263 - positive regulation of canonical Wnt signaling pathway |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
