Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 25754235, 24797263
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0000139 - Golgi membrane
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 870
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024