HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: Q53GZ6 (Q53GZ6)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)
Gene: Q53GZ6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.60	0.565

Property	Details
Experiments	unassigned2173, 20029029
Identification Methods	ubiquitin reconstruction
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 646
+	Hs
		337839 EGFR_HUMAN (1-1210): 0: 1241: 100.00		HSP7C_HUMAN (1-646): 0: 972: 99.85
+	Hs
		338019 EGFR_HUMAN (1-1210): 0: 1241: 100.00		HS71L_HUMAN (2-646): 0: 969: 82.33
+	Hs
		338520 EGFR_HUMAN (1-1210): 0: 1241: 100.00		Q59EJ3_HUMAN (1-646): 0: 961: 84.06
+	Hs
		338514 EGFR_HUMAN (1-1210): 0: 1241: 100.00		Q53FC7_HUMAN (6-646): 0: 955: 77.07
+	Hs
		337827 EGFR_HUMAN (1-1210): 0: 1241: 100.00		HS71A_HUMAN (1-646): 0: 951: 84.37
+	Hs
		338182 EGFR_HUMAN (1-1210): 0: 1241: 100.00		HSP72_HUMAN (2-646): 0: 944: 85.01
+	Hs
		383840 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		Q53FC7_HUMAN (6-646): 0: 955: 77.07
+	Hs
		503428 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		HSP7C_HUMAN (1-646): 0: 972: 99.85
+	Hs
		503499 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		HSP7C_HUMAN (1-646): 0: 972: 99.85
+	Rn
		544811 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		HSP7C_RAT (1-646): 0: 972: 99.69
+	Gg
		94427 KSYK_CHICK (718-961): 1.71e-55: 206: 41.30		HSP70_CHICK (3-646): 0: 982: 85.76
+	Hs
		503608 ABL2_HUMAN (707-974): 5.53e-52: 202: 40.37		HSP7C_HUMAN (1-646): 0: 972: 99.85
+	Gg
		94419 KSYK_CHICK (718-961): 1.71e-55: 206: 41.30		HSP7C_CHICK (1-646): 0: 965: 97.83
+	Hs
		483751 KSYK_HUMAN (716-961): 1.13e-53: 201: 41.70		HS71A_HUMAN (1-646): 0: 951: 84.37
+	Hs
		789047 ABL2_HUMAN (707-974): 5.53e-52: 202: 40.37		HSP72_HUMAN (2-646): 0: 944: 85.01
+	Hs
		435511 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		HSP7C_HUMAN (1-646): 0: 972: 99.85