Protein: RBD2
Rhomboid-type serine protease 2 (EC 3.4.21.105) (Rhomboid protein 2)

Gene: RBD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 81
UniProt ID: Q12270

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004252 - serine-type endopeptidase activity
GO:0005794 - Golgi apparatus
GO:0006508 - proteolysis
GO:0034399 - nuclear periphery

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084701

RBD2
Rhomboid-type serine protease 2

3

3

Small-scale

0.847

High

818084

TMN3
Transmembrane 9 superfamily member 3

3

2

High-throughput

0.658

High

781313

AUR1
Inositol phosphorylceramide synthase catalytic subunit AUR1

2

0

High-throughput

0.588

High

809144

AKR1
Palmitoyltransferase AKR1

2

0

High-throughput

0.588

High

863838

ATG27
Autophagy-related protein 27

2

0

High-throughput

0.587

High

806227

CTR2
Copper transport protein CTR2

2

1

High-throughput

0.559

High

484337

KEX1
Pheromone-processing carboxypeptidase KEX1

1

2

High-throughput

0.541

High

609290

CPT1
Cholinephosphotransferase 1

1

1

High-throughput

0.541

High

645119

EPT1
Choline/ethanolaminephosphotransferase 1

1

1

High-throughput

0.541

High

732207

COPG
Coatomer subunit gamma

1

3

High-throughput

0.541

High

782631

TVP38
Golgi apparatus membrane protein TVP38

1

1

High-throughput

0.541

High

801711

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

1

High-throughput

0.541

High

805175

SFB3
SED5-binding protein 3

1

2

High-throughput

0.541

High

836037

COPB
Coatomer subunit beta

1

3

High-throughput

0.541

High

836121

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.541

High

850761

COPD
Coatomer subunit delta

1

1

High-throughput

0.541

High

932641

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.541

High

1046576

GRH1
GRASP65 homolog protein 1

1

2

High-throughput

0.541

High

1047168

ERV41
ER-derived vesicles protein ERV41

1

1

High-throughput

0.541

High

546765

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.521

High

536190

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.518

High

646207

SLY1
Protein SLY1

1

0

High-throughput

0.518

High

673037

YCT3
Uncharacterized protein YCR043C

1

0

High-throughput

0.518

High

794810

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.518

High

818589

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.518

High

849671

EMP47
Protein EMP47

1

0

High-throughput

0.518

High

921495

COPZ
Coatomer subunit zeta

1

0

High-throughput

0.518

High

1043340

GOT1
Protein transport protein GOT1

1

0

High-throughput

0.518

High

1043588

ANY1
Scramblase ANY1

1

0

High-throughput

0.518

High

1044209

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.518

High

1046558

LPP1
Lipid phosphate phosphatase 1

1

0

High-throughput

0.518

High

1053580

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.518

High

1064975

SNX3
Sorting nexin-3

1

0

Small-scale

0.518

High

625934

HNM1
Choline transporter

1

2

High-throughput

0.494

High

744943

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

1

High-throughput

0.494

High

745060

YSC84
Protein YSC84

1

5

High-throughput

0.494

High

793255

BAP2
Leu/Val/Ile amino-acid permease

1

1

High-throughput

0.494

High

805450

BZZ1
Protein BZZ1

1

1

High-throughput

0.494

High

850507

LSB3
LAS seventeen-binding protein 3

1

4

High-throughput

0.494

High

376354

YPT1
GTP-binding protein YPT1

1

0

High-throughput

0.486

High

698198

KTR1
Alpha-1,2 mannosyltransferase KTR1

1

1

High-throughput

0.479

High

794063

KTR3
Probable mannosyltransferase KTR3

1

1

High-throughput

0.479

High

811558

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

1

High-throughput

0.479

High

1084374

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

564770

ATC1
Calcium-transporting ATPase 1

1

0

High-throughput

0.458

High

743931

GDA1
Guanosine-diphosphatase

1

0

High-throughput

0.458

High

792709

GLRX7
Monothiol glutaredoxin-7

1

0

High-throughput

0.458

High

797669

GDT1
Divalent cation/proton antiporter GDT1

1

0

High-throughput

0.458

High

803106

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.458

High

863595

MNN5
Alpha-1,2-mannosyltransferase MNN5

1

0

High-throughput

0.458

High

863622

MNN11
Probable alpha-1,6-mannosyltransferase MNN11

1

0

High-throughput

0.458

High

916574

YIP1
Protein transport protein YIP1

1

0

High-throughput

0.458

High

1084296

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.458

High

470163

SPS1
Sporulation-specific protein 1

1

1

High-throughput

0.457

High

810678

SSN3
Meiotic mRNA stability protein kinase SSN3

1

2

High-throughput

0.457

High

1042324

PKH3
Serine/threonine-protein kinase PKH3

1

1

High-throughput

0.457

High

528031

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.437

High

728663

OCH1
Initiation-specific alpha-1,6-mannosyltransferase

1

1

High-throughput

0.437

High

744072

ANP1
Mannan polymerase II complex ANP1 subunit

1

1

High-throughput

0.437

High

811586

MNN9
Mannan polymerase complexes subunit MNN9

1

1

High-throughput

0.437

High

826340

EPS1
ER-retained PMA1-suppressing protein 1

1

2

High-throughput

0.437

High

865830

HOC1
Putative glycosyltransferase HOC1

1

1

High-throughput

0.437

High

917246

AIM14
Probable metalloreductase AIM14

1

1

High-throughput

0.437

High

525566

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

742690

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

748250

VAM7
Vacuolar morphogenesis protein 7

2

0

Small-scale

0.323

High

805289

YPT35
Endosomal/vacuolar adapter protein YPT35

2

0

Small-scale

0.323

High

603603

ERS1
Cystine transporter

2

0

High-throughput

0.319

High

827108

GST1
Glutathione S-transferase 1

2

0

High-throughput

0.319

High

1084703

LAS17
Proline-rich protein LAS17

2

0

High-throughput

0.307

High

916788

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.282

High

932794

DOS2
Protein DOS2

1

0

High-throughput

0.282

High

1043886

YMB8
Uncharacterized vacuolar membrane protein YML018C

1

0

High-throughput

0.282

High

758346

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.261

Low

708545

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

830071

CDC1
Cell division control protein 1

1

0

High-throughput

0.249

Low

1056391

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

1084702

ERV2
FAD-linked sulfhydryl oxidase ERV2

1

0

High-throughput

0.249

Low

393531

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.238

Low

653917

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025