Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: TENS3 (Q68CZ2)
Tensin-3 (EC 3.1.3.-) (Tensin-like SH2 domain-containing protein 1) (Tumor endothelial marker 6)
Gene: TNS3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.87 | 1.00 | 0.937 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15140944, 25402006, 24658140, 22973453, unassigned2173 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, protein complementation assay, luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation, ubiquitin reconstruction |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2 |
| Common GO terms | GO:0005925 - focal adhesion |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
