Protein: SC23B
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)

Gene: SC23B, SEC23B
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q15437

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

319101

SC24D
Protein transport protein Sec24D

10

15

Small-scale

0.978

High

925720

SC24C
Protein transport protein Sec24C

6

16

Small-scale

0.946

High

338334

SC24A
Protein transport protein Sec24A

4

16

Small-scale

0.892

High

338478

SC24B
Protein transport protein Sec24B

4

16

Small-scale

0.892

High

1148888

SC23A
Protein transport protein Sec23A

3

17

High-throughput

0.858

High

1149032

SAR1A
Small COPII coat GTPase SAR1A

2

13

Small-scale

0.754

High

1148974

SC23B
Protein transport protein Sec23B

1

17

High-throughput

0.698

High

175055

SC16A
Protein transport protein Sec16A

3

17

Small-scale

0.667

High

1149047

SAR1B
Small COPII coat GTPase SAR1B

1

15

High-throughput

0.618

High

1113180

CUL3
Cullin-3

2

7

High-throughput

0.611

High

807436

IF4A3
Eukaryotic initiation factor 4A-III

2

2

High-throughput

0.601

High

1149048

S23IP
SEC23-interacting protein

2

10

High-throughput

0.601

High

241766

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

323875

SC31A
Protein transport protein Sec31A

2

8

Small-scale

0.584

High

1148982

KLH12
Kelch-like protein 12

2

2

Small-scale

0.584

High

480151

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.580

High

1116652

RIN1
Ras and Rab interactor 1

2

0

High-throughput

0.580

High

1149016

PRRC1
Protein PRRC1

2

9

High-throughput

0.578

High

1149011

FBXW5
F-box/WD repeat-containing protein 5

2

0

Small-scale

0.577

High

1149027

PACER
Protein associated with UVRAG as autophagy enhancer

2

1

High-throughput

0.574

High

1148994

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

11

High-throughput

0.573

High

1149009

FATE1
Fetal and adult testis-expressed transcript protein

1

1

High-throughput

0.573

High

1102327

GRB10
Growth factor receptor-bound protein 10

2

3

High-throughput

0.571

High

1149038

PD1L1
Programmed cell death 1 ligand 1

1

3

High-throughput

0.553

High

1006422

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.550

High

1149017

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.550

High

987660

GRB2
Growth factor receptor-bound protein 2

2

0

High-throughput

0.547

High

1149022

TRI55
Tripartite motif-containing protein 55

1

9

High-throughput

0.541

High

483098

CLCA
Clathrin light chain A

1

2

High-throughput

0.536

High

505163

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

1

High-throughput

0.536

High

563811

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

691031

1433T
14-3-3 protein theta

1

12

High-throughput

0.536

High

729860

1433B
14-3-3 protein beta/alpha

1

12

High-throughput

0.536

High

813097

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.536

High

876872

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.536

High

966343

1433G
14-3-3 protein gamma

1

12

High-throughput

0.536

High

971555

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

1049315

1433F
14-3-3 protein eta

1

12

High-throughput

0.536

High

1148995

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1149002

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.536

High

1149013

BTBD6
BTB/POZ domain-containing protein 6

1

3

High-throughput

0.536

High

1149019

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

3

High-throughput

0.536

High

1149026

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1149028

PKHA3
Pleckstrin homology domain-containing family A member 3

1

7

High-throughput

0.536

High

1149031

SRA1
Steroid receptor RNA activator 1

1

4

High-throughput

0.536

High

411985

NTRK1
High affinity nerve growth factor receptor

2

20

High-throughput

0.533

High

1148999

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

3

High-throughput

0.523

High

830794

CCNF
Cyclin-F

1

4

High-throughput

0.515

High

843581

HD
Huntingtin

1

1

High-throughput

0.515

High

1148976

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

508018

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

987362

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

Small-scale

0.501

High

389384

FINC
Fibronectin

1

2

High-throughput

0.489

High

1149010

TRI63
E3 ubiquitin-protein ligase TRIM63

1

7

High-throughput

0.481

High

125475

LEG9
Galectin-9

1

4

High-throughput

0.479

High

172843

XPO1
Exportin-1

1

10

High-throughput

0.479

High

176473

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

179907

BET1
BET1 homolog

1

6

High-throughput

0.479

High

181794

EPHB6
Ephrin type-B receptor 6

1

20

High-throughput

0.479

High

363324

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

372105

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.479

High

410862

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.479

High

431819

ITB1
Integrin beta-1

1

1

Small-scale

0.479

High

488798

FURIN
Furin

1

3

High-throughput

0.479

High

520072

ANDR
Androgen receptor

1

4

High-throughput

0.479

High

541505

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

593378

PGFRA
Platelet-derived growth factor receptor alpha

1

20

High-throughput

0.479

High

611135

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

4

High-throughput

0.479

High

648520

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

695541

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

698685

CALX
Calnexin

1

3

High-throughput

0.479

High

710839

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.479

High

714142

PML
Protein PML

1

5

High-throughput

0.479

High

767217

MERL
Merlin

1

2

High-throughput

0.479

High

799142

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

849179

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.479

High

879125

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

888089

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

904754

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

931854

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.479

High

938220

SEC13
Protein SEC13 homolog

1

10

Small-scale

0.479

High

970558

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

1022164

DAB2
Disabled homolog 2

1

1

Small-scale

0.479

High

1031387

IFM3
Interferon-induced transmembrane protein 3

1

9

High-throughput

0.479

High

1099924

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.479

High

1107742

SQSTM
Sequestosome-1

1

5

High-throughput

0.479

High

1122491

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

1128727

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

1132022

STAT4
Signal transducer and activator of transcription 4

1

2

High-throughput

0.479

High

1138239

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1148975

STIL
SCL-interrupting locus protein

1

1

High-throughput

0.479

High

1148978

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

1148990

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1148991

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.479

High

1148993

PATL1
Protein PAT1 homolog 1

1

11

High-throughput

0.479

High

1149000

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

8

High-throughput

0.479

High

1149001

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1149004

SMAP2
Stromal membrane-associated protein 2

1

1

High-throughput

0.479

High

1149007

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1149014

SNX27
Sorting nexin-27

1

3

High-throughput

0.479

High

1149015

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1149020

LZTS2
Leucine zipper putative tumor suppressor 2

1

3

High-throughput

0.479

High

1149029

CPAP
Centrosomal P4.1-associated protein

1

3

High-throughput

0.479

High

1149030

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

12

High-throughput

0.479

High

1149039

TM216
Transmembrane protein 216

1

1

High-throughput

0.479

High

1149041

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1149042

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

1149043

GGA2
ADP-ribosylation factor-binding protein GGA2

1

1

Small-scale

0.479

High

1149046

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

8

High-throughput

0.479

High

1140317

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1149024

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

328025

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

17

High-throughput

0.445

High

400877

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.445

High

943520

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

1

High-throughput

0.445

High

952183

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

17

High-throughput

0.445

High

1148983

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1148985

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.445

High

1149003

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

1

High-throughput

0.445

High

139876

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

3

High-throughput

0.437

High

179611

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

20

High-throughput

0.437

High

188895

TMPS2
Transmembrane protease serine 2

1

5

High-throughput

0.437

High

218212

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

315621

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.437

High

352449

TOP3B
DNA topoisomerase 3-beta-1

1

3

High-throughput

0.437

High

406215

MYCN
N-myc proto-oncogene protein

1

10

High-throughput

0.437

High

439744

INSR
Insulin receptor

1

20

High-throughput

0.437

High

463973

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

465530

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.437

High

560404

IFM1
Interferon-induced transmembrane protein 1

1

9

High-throughput

0.437

High

588776

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

657584

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.437

High

710256

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.437

High

710710

EPHA8
Ephrin type-A receptor 8

1

20

High-throughput

0.437

High

766581

PHB1
Prohibitin 1

1

1

High-throughput

0.437

High

768270

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

777692

VGFR3
Vascular endothelial growth factor receptor 3

1

20

High-throughput

0.437

High

932076

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.437

High

1008037

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

2

High-throughput

0.437

High

1034241

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.437

High

1114840

CUL4A
Cullin-4A

1

7

High-throughput

0.437

High

1118035

DX39B
Spliceosome RNA helicase DDX39B

1

3

Small-scale

0.437

High

1147325

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.437

High

1148977

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.437

High

1148980

DDR2
Discoidin domain-containing receptor 2

1

20

High-throughput

0.437

High

1148984

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

1148986

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.437

High

1148992

TM11B
Transmembrane protease serine 11B

1

5

High-throughput

0.437

High

1148996

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

1149005

CLC4D
C-type lectin domain family 4 member D

1

8

High-throughput

0.437

High

1149008

ATOH1
Transcription factor ATOH1

1

1

Small-scale

0.437

High

1149012

S2546
Mitochondrial outer membrane protein SLC25A46

1

3

High-throughput

0.437

High

1149025

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

1149033

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.437

High

1149034

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.437

High

1149035

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

1149036

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.437

High

1149040

EPHA6
Ephrin type-A receptor 6

1

20

High-throughput

0.437

High

1149044

CLC4E
C-type lectin domain family 4 member E

1

8

High-throughput

0.437

High

1149045

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.437

High

1148988

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

Small-scale

0.426

High

664975

ERD21
ER lumen protein-retaining receptor 1

1

1

Small-scale

0.408

High

888877

TMEDA
Transmembrane emp24 domain-containing protein 10

1

17

Small-scale

0.408

High

992188

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.408

High

1083171

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

1

Small-scale

0.408

High

1105844

TMED1
Transmembrane emp24 domain-containing protein 1

1

14

Small-scale

0.408

High

1146548

TMED2
Transmembrane emp24 domain-containing protein 2

1

16

Small-scale

0.408

High

1149021

TMED9
Transmembrane emp24 domain-containing protein 9

1

17

Small-scale

0.408

High

653335

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.407

High

1148987

ZNT6
Zinc transporter 6

1

3

High-throughput

0.407

High

1149018

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

1

High-throughput

0.407

High

1149023

GTR11
Solute carrier family 2, facilitated glucose transporter member 11

1

2

High-throughput

0.407

High

647464

UD11
UDP-glucuronosyltransferase 1A1

1

0

Small-scale

0.391

High

214507

HXA3
Homeobox protein Hox-A3

2

0

High-throughput

0.334

High

1148997

SYNE4
Nesprin-4

1

0

High-throughput

0.299

High

1111003

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1148989

FA83H
Protein FAM83H

1

0

High-throughput

0.279

Low

1148981

S2535
Solute carrier family 25 member 35

1

0

High-throughput

0.249

Low

1148998

HROB
Homologous recombination OB-fold protein

1

0

Small-scale

0.249

Low

1149037

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

888518

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1149006

SSH1
Protein phosphatase Slingshot homolog 1

1

0

High-throughput

0.232

Low

1148979

MA2A1
Alpha-mannosidase 2

1

0

Small-scale

0.213

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025