HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: QSOX2 (Q6ZRP7)
Sulfhydryl oxidase 2 (EC 1.8.3.2) (Neuroblastoma-derived sulfhydryl oxidase) (Quiescin Q6-like protein 1)
Gene: QSOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 698
+	Hs
		337993 EGFR_HUMAN (1-1210): 0: 1241: 100.00		PDIA3_HUMAN (38-570): 6.98e-111: 346: 12.32
+	Hs
		337778 EGFR_HUMAN (1-1210): 0: 1241: 100.00		PDIA1_HUMAN (19-174): 7.79e-32: 131: 21.80
+	Hs
		338668 EGFR_HUMAN (1-1210): 0: 1241: 100.00		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		338707 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TXND5_HUMAN (28-180): 6.57e-29: 122: 20.61
+	Hs
		383571 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		531718 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		383876 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		411415 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		QSOX2_HUMAN (10-698): 0: 680: 100.00
+	Rn
		514117 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		PDIA3_RAT (38-570): 5.53e-107: 336: 12.13
+	Hs
		411391 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		PDIA6_HUMAN (36-423): 6.73e-65: 223: 14.62
+	Rn
		544870 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		PDIA6_RAT (36-423): 5.31e-65: 223: 15.08
+	Hs
		434126 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		531732 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		411285 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		411271 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		PDIA1_HUMAN (19-174): 7.79e-32: 131: 21.80
+	Rn
		388065 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		PDIA1_RAT (19-206): 2.53e-31: 130: 19.58
+	Hs
		411430 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		411442 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		TXND5_HUMAN (28-180): 6.57e-29: 122: 20.61
+	Rn
		102493 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		G3V6T7_RAT (448-556): 4.91e-09: 61.5: 11.71
+	Gg
		94496 KSYK_CHICK (718-961): 1.71e-55: 206: 41.30		PDIA3_CHICK (50-198): 4.01e-29: 123: 16.78