HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: CGS5 (P30283)
S-phase entry cyclin-5
Gene: CLB5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 9346238, 9831566, 11545745, 27068241, 25602519, 28650257, 18563728, 37968396, 23751495, 25287299, 20865002, 23230424, 10848604, 15200949, 16554755, 32851976, 37428921, 20489023, 21658602, 25049391 and 2 others

more...
Identification Methods affinity chromatography technology, biochemical, pull down, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 298
Sc

1 435
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Xl
+ Hs
+ Mm
+ Gg
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024