HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: FAB1 (P34756)
1-phosphatidylinositol 3-phosphate 5-kinase FAB1 (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (Formation of aploid and binucleate cells protein 1) (Styryl dye vacuolar localization protein 7) (Type III PIP kinase) (PIPkin-III)
Gene: FAB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24374311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 298 Sc			1 2278
+	Sc
		565532 PHO85_YEAST (6-297): 2.21e-126: 364: 52.67		FAB1_YEAST (1-2278): 0: 2030: 100.00
+	Hs
		625228 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		TCPG_HUMAN (656-1193): 5.56e-166: 523: 14.88
+	Hs
		625220 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		TCPE_HUMAN (647-1174): 1.32e-164: 519: 12.72
+	Hs
		573132 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		TCPA_HUMAN (661-1182): 3.83e-154: 491: 11.50
+	Hs
		625579 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		TCPH_HUMAN (661-1192): 1.64e-153: 489: 12.32
+	Hs
		414817 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		TCPE_HUMAN (647-1174): 1.32e-164: 519: 12.72
+	Hs
		826623 CDK5_HUMAN (5-297): 3.81e-134: 383: 55.10		TCPG_HUMAN (656-1193): 5.56e-166: 523: 14.88
+	Hs
		821173 CDK5_HUMAN (5-297): 3.81e-134: 383: 55.10		TCPE_HUMAN (647-1174): 1.32e-164: 519: 12.72
+	Hs
		414725 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		TCPA_HUMAN (661-1182): 3.83e-154: 491: 11.50
+	Hs
		415042 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		TCPH_HUMAN (661-1192): 1.64e-153: 489: 12.32
+	Hs
		573225 CDK5_HUMAN (5-297): 3.81e-134: 383: 55.10		TCPA_HUMAN (661-1182): 3.83e-154: 491: 11.50
+	Hs
		960322 CDK5_HUMAN (5-297): 3.81e-134: 383: 55.10		TCPH_HUMAN (661-1192): 1.64e-153: 489: 12.32
+	Hs
		625246 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		TCPD_HUMAN (685-1181): 4.03e-112: 370: 15.50
+	Sc
		339390 CDK1_YEAST (1-298): 1.93e-142: 404: 100.00		TCPA_YEAST (674-1178): 1.07e-112: 373: 13.88
+	Hs
		414827 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		TCPD_HUMAN (685-1181): 4.03e-112: 370: 15.50
+	Hs
		843162 CDK5_HUMAN (5-297): 3.81e-134: 383: 55.10		TCPD_HUMAN (685-1181): 4.03e-112: 370: 15.50
+	Hs
		414854 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		PI42B_HUMAN (1988-2208): 3.85e-54: 198: 24.11
+	Hs
		415003 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		PI42C_HUMAN (1988-2205): 2.71e-53: 195: 24.55
+	Hs
		960350 CDK5_HUMAN (5-297): 3.81e-134: 383: 55.10		FYV1_HUMAN (100-563): 5.88e-42: 172: 17.98