HitPredict

Interactor 1: KPYK1 (P00549)
Pyruvate kinase 1 (PK 1) (EC 2.7.1.40) (cell division cycle protein 19)
Gene: CDC19

Interactor 2: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	26217697, 26804907, 25452130, 31399574, 24488121, 37968396, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 500 Sc			1 709
+	Hs
		437856 KPYM_HUMAN (2-500): 0: 741: 50.10		HS90B_HUMAN (5-709): 0: 1026: 62.13
+	Hs
		431489 KPYM_HUMAN (2-500): 0: 741: 50.10		HS90A_HUMAN (4-709): 0: 1015: 60.83
+	Sc
		339995 KPYK1_YEAST (1-500): 0: 712: 100.00		HSC82_YEAST (1-709): 0: 973: 94.64
+	Ca
		804464 KPYK_CANAL (2-499): 0: 704: 72.40		HSP90_CANAL (4-709): 0: 959: 81.75
+	Sc
		366596 KPYK2_YEAST (2-500): 0: 667: 70.94		HSP82_YEAST (1-709): 0: 984: 100.00